Title:
細胞性免疫を誘導する経鼻ワクチン
Document Type and Number:
Japanese Patent JP7445897
Kind Code:
B2
Abstract:
The present invention provides a nanogel nasal vaccine that induces cell-mediated immunity. Specifically, the present invention relates to a vaccine preparation comprising a complex of a nanogel, a vaccine antigen, and an adjuvant, wherein the vaccine preparation can efficiently induce the cell-mediated immunity, and can also induce a systemic and mucosal immune response.
Inventors:
Yoshikazu Sachi
Rika Nakahashi
Hiroshi Seino
Rika Nakahashi
Hiroshi Seino
Application Number:
JP2020534761A
Publication Date:
March 08, 2024
Filing Date:
August 02, 2019
Export Citation:
Assignee:
National University Corporation The University of Tokyo
HanaVax Co., Ltd.
HanaVax Co., Ltd.
International Classes:
A61K39/39; A61K9/06; A61K9/51; A61K39/00; A61K39/04; A61K39/12; A61P37/04; A61P43/00
Domestic Patent References:
| JP2010105968A | ||||
| JP2016520530A | ||||
| JP2010531820A | ||||
| JP2016503029A |
Foreign References:
| WO2017170494A1 | ||||
| WO1998009650A1 |
Other References:
医学のあゆみ,2018年02月03日,Vol.264(5),pp.411-418
Mol. Immunol.,2018年06月,Vol.98,pp.19-24
MucosalImmunology,2017年,Vol.10(5),pp.1351-1360
Journal of Hypertension,2018年02月,Vol.36,pp.387-394
PLOS ONE,2014年,Vol.9, Issue 8, e104824,pp.1-8
Vaccine,2011年,Vol.29,pp.5210-5220
PLOS ONE,2014年,Vol.9, Issue 10, e110150,pp.1-7
VIRAL IMMUNOLOGY,2017年,Vol.30(6),pp.463-470
Mol. Immunol.,2018年06月,Vol.98,pp.19-24
MucosalImmunology,2017年,Vol.10(5),pp.1351-1360
Journal of Hypertension,2018年02月,Vol.36,pp.387-394
PLOS ONE,2014年,Vol.9, Issue 8, e104824,pp.1-8
Vaccine,2011年,Vol.29,pp.5210-5220
PLOS ONE,2014年,Vol.9, Issue 10, e110150,pp.1-7
VIRAL IMMUNOLOGY,2017年,Vol.30(6),pp.463-470
Attorney, Agent or Firm:
Koji Okuhara
Sumito Sekimoto
Sumito Sekimoto
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