Title:
代謝型グルタミン酸受容体の負のアロステリックモジュレーター（ＮＡＭＳ）とその使用
Document Type and Number:
Japanese Patent JP6552061
Kind Code:
B2
Abstract:
Provided herein are small molecule active metabotropic glutamate subtype-2 and -3 receptor negative allosteric modulators (NAMs), compositions comprising the compounds, and methods of using the compounds and compositions.
Inventors:
Cosford, Nicholas David, Peter
La Bean Dra-Panical, Danha
Schaeffler, Douglas, Jay.
La Bean Dra-Panical, Danha
Schaeffler, Douglas, Jay.
Application Number:
JP2016570862A
Publication Date:
July 31, 2019
Filing Date:
June 09, 2015
Export Citation:
Assignee:
Sanford-Burnham Medical Research Institute
International Classes:
C07D233/64; A61K31/341; A61K31/381; A61K31/415; A61K31/4164; A61K31/4196; A61K31/42; A61K31/421; A61K31/4245; A61K31/425; A61K31/426; A61K31/433; A61K31/4439; A61K31/505; A61K31/506; A61P17/00; A61P21/00; A61P25/00; A61P25/04; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P29/02; A61P35/00; A61P43/00; C07D231/12; C07D239/26; C07D249/08; C07D261/08; C07D263/32; C07D271/06; C07D275/02; C07D277/26; C07D277/30; C07D285/08; C07D307/54; C07D333/24; C07D401/04; C07D401/14; C07D403/04; C07D403/10; C07D405/04; C07D405/10; C07D409/04; C07D409/14; C07D413/04; C07D413/14; C07D417/04; C07D417/10; C07D417/14
Domestic Patent References:
| JP2006516110A | ||||
| JP2008543971A | ||||
| JP2009531370A | ||||
| JP2010524852A | ||||
| JP2006522128A | ||||
| JP2004536037A | ||||
| JP2005526081A | ||||
| JP2005522440A | ||||
| JP2004525965A |
Foreign References:
| WO2011116356A1 | ||||
| WO2013033246A1 | ||||
| WO2009153665A1 |
Other References:
SYNTHESIS,2013年,45,pp.75-84
Attorney, Agent or Firm:
Kazuhiro Kiyohara