Title:
NEURITE OUTGROWTH INHIBITOR, PAIN INHIBITOR AND ITCH INHIBITOR
Document Type and Number:
Japanese Patent JP2015205858
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a neurite outgrowth inhibitor which can inhibit neurite outgrowth and can inhibit hyperalgesia and itch irritation by outgrowth of primary sensory neurons.SOLUTION: A neurite outgrowth inhibitor of the invention contains at least one kind of herbal medicines having a neuronal cell projection outgrowth-inhibiting activity in a dorsal root ganglion (DRG) by a nerve growth factor (NGF), and can inhibit various symptoms caused by neurite outgrowth, such as hyperalgesia and itch irritation due to outgrowth of primary sensory neurons.
Inventors:
NAKAMURA GENICHI
WATABE SHINPEI
MURAYAMA CHIAKI
NORIMOTO HISAYOSHI
WATABE SHINPEI
MURAYAMA CHIAKI
NORIMOTO HISAYOSHI
Application Number:
JP2014089089A
Publication Date:
November 19, 2015
Filing Date:
April 23, 2014
Export Citation:
Assignee:
KRACIE SEIYAKU KK
MEDICAL CORP NAKAMURA DERMATOLOGY CLINIC
MEDICAL CORP NAKAMURA DERMATOLOGY CLINIC
International Classes:
A61K36/18; A61K36/07; A61K36/23; A61K36/25; A61K36/28; A61K36/48; A61K36/53; A61K36/71; A61K36/73; A61K36/75; A61K36/899; A61P17/04; A61P25/00; A61P29/00; A61P43/00
Domestic Patent References:
| JP2007186457A | 2007-07-26 | |||
| JP2003342184A | 2003-12-03 |
Foreign References:
| WO2014065194A1 | 2014-05-01 |
Other References:
SAMUKAWA, KEIICHIら: "Red ginseng inhibits scratching behavior associated with atopic dermatitis in experimental anima", JOURNAL OF PHARMACOLOGICAL SCIENCES (TOKYO, JAPAN) (2012), 118(3), 391-400, JPN6017024793, 2012, ISSN: 0003591711
KOICHIRO NAKANISHI ET.AL: "Shishihakuhito, a Kampo medicine for atopic dermatitis, suppresses NGF-induced neurite extension by", JOURNAL OF TRADITIONAL MEDICINES　VOL. 28 (2011) NO. 1 P 16-21, JPN6017024794, 2011, ISSN: 0003591712
KOICHIRO NAKANISHI ET.AL: "Shishihakuhito, a Kampo medicine for atopic dermatitis, suppresses NGF-induced neurite extension by", JOURNAL OF TRADITIONAL MEDICINES　VOL. 28 (2011) NO. 1 P 16-21, JPN6017024794, 2011, ISSN: 0003591712
Attorney, Agent or Firm:
Rei Aihara
Moriwaki Rio
Moriwaki Rio