Title:
中性子捕捉製剤およびその用途
Document Type and Number:
Japanese Patent JP4990137
Kind Code:
B2
Abstract:
In order to improve the safety of neutron capture therapy, a neutron capture preparation is provided which can be accumulated in a tumor cell at a good level. A boron compound is used as a neutron-capturing agent. A W/O/W-type emulsion is formed which is composed of an inner aqueous phase containing the boron compound, an oily phase and an outer aqueous phase, and the emulsion can be used as the neutron capture preparation. Examples of the boron compound include borocaptate (BSH) and p-boronophenylalanin.
Inventors:
Hironobu Yanagi
Masazumi Eriguchi
Ryohei Nishimura
Hideshi Azuma
Tetsuya Kajiyama
Masazumi Eriguchi
Ryohei Nishimura
Hideshi Azuma
Tetsuya Kajiyama
Application Number:
JP2007526916A
Publication Date:
August 01, 2012
Filing Date:
July 28, 2006
Export Citation:
Assignee:
Hironobu Yanagi
International Classes:
A61K31/69; A61K9/113; A61K33/22; A61K47/34; A61K47/44; A61P1/16; A61P35/00
Domestic Patent References:
| JPH10158152A | 1998-06-16 |
Attorney, Agent or Firm:
Koichiro Tsujimaru
Yumi Nakayama
Reiko Yoshida
Yumi Nakayama
Reiko Yoshida