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Title:
NEW COMPOUND WF15483, PRODUCTION AND USE THEREOF
Document Type and Number:
Japanese Patent JPH1080291
Kind Code:
A
Abstract:

To obtain the subject new compound manifesting an antifungal activity, capable of being used as a fungicide in the fields of a medicine, an agrochemical and a cleaning product and especially useful as a therapeutic agent for a fungal infections disease, etc., by culturing a WF15483 producing strain belonging to mold fungi in a medium.

This new compound WF15483 is two compound consisting of (A) WF15483A having an appearance of a colorless powder, a molecular formula of C60H97N15O21, 115-119°C (decomposition) melting point, 1364.53 molecular weight [FAB-MS: m/z 1387 (M+Na)], solubilities of hardly soluble to water, methanol and acetonitrile, and insoluble to n-hexane, color development reactivities of positive in reactions with iodine vapor and cerium sulfate, pseudo positive in reactions to ninhydrin and ferric chloride and negative in reactions to Dragendorff's and Molische's and (B) WF15483B having similar appearance, solubilities, and color development reactions, a molecular formula of C59H75N15O21, 1350.50 molecular weight [FAB-MS; m/z 1373 (M+Na)], and obtained by culturing a mold fungus strain No.15483 (FERMBP-5526) in a medium.


Inventors:
HASHIMOTO MICHIMASA
TSURUMI YASUHISA
TAKASE SHIGEHIRO
KINO TORU
HASHIMOTO MASAHARU
Application Number:
JP14051597A
Publication Date:
March 31, 1998
Filing Date:
May 29, 1997
Export Citation:
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Assignee:
FUJISAWA PHARMACEUTICAL CO
International Classes:
C12P1/02; A61K36/06; A61P31/04; C07G11/00; C12N1/14; C12R1/645; (IPC1-7): C12P1/02; A61K35/70; C07G11/00; C12N1/14
Attorney, Agent or Firm:
Takashima Hajime