Title:
新規なジテルペン化合物
Document Type and Number:
Japanese Patent JP4465432
Kind Code:
B2
Abstract:
The present invention provides a novel diterpene compounds with antineoplastic activities. The novel diterpene compounds of the present invention are represented by the general formula (I). R1 to R6 in the formula represent an aliphatic group, or a radical represented by the general formula RCO-, wherein R represents an aliphatic, an aromatic or a heteroaromatic group. The compounds of the present invention may be prepared by extracting roots of Euphorbia kansui L. with an organic solvent such as chloroform, ethyl acetate and butanol. These extracted compounds may be used as starting materials for the preparation of the compounds represented by the general formula (I). The compounds of the present invention have antineoplastic activities, and therefore, useful as antineoplastic agents.
Inventors:
Kita Nakashin
Miyata Shohei
Royal rock
Nori
Newborn baby
Miyata Shohei
Royal rock
Nori
Newborn baby
Application Number:
JP2003201340A
Publication Date:
May 19, 2010
Filing Date:
July 24, 2003
Export Citation:
Assignee:
NIHON UNIVERSITY
International Classes:
C07D493/08; A61K31/34; A61P35/00; C07D493/04
Domestic Patent References:
| JP2003171349A | ||||
| JP7149633A |
Other References:
HIRATA, Y.,Pure and Applied Chemistry,1975年,Vol.41, No.1-2,p.175-199
Attorney, Agent or Firm:
Minoru Nakamura
Fumiaki Otsuka
Sadao Kumakura
Shishido Kaichi
Toshio Imajo
Nobuo Ogawa
Village shrine Atsuo
Takaki Nishijima
Atsushi Hakoda
Koji Hirayama
Fumiaki Otsuka
Sadao Kumakura
Shishido Kaichi
Toshio Imajo
Nobuo Ogawa
Village shrine Atsuo
Takaki Nishijima
Atsushi Hakoda
Koji Hirayama