Title:
New effective Tapentador dosage forms
Document Type and Number:
Japanese Patent JP6216489
Kind Code:
B2
Abstract:
The present invention provides a dosage form comprising at least one form of tapentadol, with or without a second analgesic, and at least one opioid antagonist, wherein tapentadol is present in an optimal or suboptimal amount and the said antagonist is present in an amount effective to improve the efficacy and or reduce the side effects of tapentadol. The present invention further provides a method of treating pain and pain related conditions by administering to a patient in need thereof, a dosage form comprising at least one form of tapentadol, with or without a second analgesic, and at least one opioid antagonist, wherein tapentadol is present in an optimal or suboptimal amount and the said antagonist is present in an amount effective to improve the efficacy and or reduce the side effects of tapentadol.
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Inventors:
Sesha Ramesh
Application Number:
JP2011534509A
Publication Date:
October 18, 2017
Filing Date:
October 29, 2009
Export Citation:
Assignee:
Grunenthal Gesellschaft Mito Beschlenktel Haftung
International Classes:
A61K31/137; A61K31/485; A61K45/00; A61P25/04; A61P39/00; A61P43/00
Other References:
The Journal of Pharmacology and Experimental Therapeutics ,2007年,Vol.323, No.1,p.265-276
Attorney, Agent or Firm:
Mitsufumi Esaki
Blacksmith
Katsunori Uenishi
Blacksmith
Katsunori Uenishi