Title:
NEW ISOFLAVONE GLYCOSIDE AND COSMETIC CONTAINING THE SAME
Document Type and Number:
Japanese Patent JP3271840
Kind Code:
B2
Abstract:
PURPOSE: To obtain the subject compound which is a new isoflavone glycoside having an excellent whitening effect on the skin and an excellent preventive and therapeutic effect on a spot or a ephelis caused by sunburn, etc., and useful as a cosmetic material for cream, emulsion, lotion, etc.
CONSTITUTION: A new isoflavone glycoside (e.g. 6''-O-apiosylpuerarin-4'-O- glycoside) represented by the formula (R1 is apiosyl, glucosyl or H; R2 is H or OH; R3 is H or glucosyl), having an excellent whitening effect on the skin and an excellent preventive and therapeutic effect on a spot or a freckle caused by sunburn, etc., and useful as a raw material for a cream-, ointment-, emulsion-, lotion-, solution-, gel-, pack- or stick-shaped cosmetic. This compound is obtained by extracting an extract from tapioca roots with 20% aqueous ethanol, treating the resultant extract with an adsorption resin column, eluting it with methanol and purifying the eluted fraction by the medium-pressure reverse phase chromatography.
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Inventors:
Yuusuke Shibuya
Yoshinori Nishizawa
Yoshinori Nishizawa
Application Number:
JP30507393A
Publication Date:
April 08, 2002
Filing Date:
December 06, 1993
Export Citation:
Assignee:
Kao Corporation
International Classes:
C07H15/26; A61K8/00; A61K8/30; A61K8/33; A61K8/49; A61K8/60; A61K8/67; A61K8/96; A61K8/98; A61Q19/00; A61Q19/02; (IPC1-7): C07H15/26; A61K7/00; A61K7/48
Domestic Patent References:
| JP5229931A | ||||
| JP6416709A | ||||
| JP4282305A |
Other References:
Ｐｈｙｔｏｃｈｅｍｉｓｔｒｙ，Ｖｏｌ．２５，Ｎｏ．７，１９８６，ｐ．１７７２−１７７５
Ｐｌａｎｔａ ｍｅｄｉｃａ，１９８８，ｐ．２５０−２５４
Ｐｌａｎｔａ ｍｅｄｉｃａ，１９８８，ｐ．２５０−２５４
Attorney, Agent or Firm:
Miyuki Ariga (3 outside)