Title:
新規の徐放性経口製剤
Document Type and Number:
Japanese Patent JP2005504051
Kind Code:
A
Abstract:
The present invention relates to an extended release oral dosage form of a pharmaceutically active substance, (R)-3-N,N-dicyclobutylamino-8-fluoro-3,4-dihydro-2H-1-benzopyran-5-carboxamide, in the form of the free base or pharmaceutically acceptable salts and/or hydrates or solvates thereof. Furthermore, the invention relates to an extended release oral dosage form that provides a defined blood concentration profile having no rapid initial rise in blood plasma concentration of said active substance when administered at low dose. The invention further relates to processes for preparing said dosage form, the use of said dosage form and a method of prevention and/or treatment of CNS disorders and related medical disturbances using said dosage form.
Inventors:
Carlin Elstrem
Woolf Herberg
Hokan Nikvist
Anika schweighofer
Marita Temsa Mani
Woolf Herberg
Hokan Nikvist
Anika schweighofer
Marita Temsa Mani
Application Number:
JP2003522502A
Publication Date:
February 10, 2005
Filing Date:
August 28, 2002
Export Citation:
Assignee:
ASTRAZENECA AKTIEBOLAG
International Classes:
A61K9/20; A61K9/22; A61K9/32; A61K9/34; A61K31/353; A61K47/32; A61K47/34; A61K47/38; A61P1/00; A61P7/12; A61P9/00; A61P13/10; A61P25/00; A61P25/04; A61P25/22; A61P25/24; A61P25/28; A61P35/00; A61K9/28; (IPC1-7): A61K9/22; A61K9/32; A61K9/34; A61K31/353; A61K47/32; A61K47/34; A61K47/38; A61P1/00; A61P7/12; A61P9/00; A61P13/10; A61P25/00; A61P25/22; A61P25/24; A61P25/28; A61P35/00
Attorney, Agent or Firm:
Chika Takagi
Junji Yuda
Shoji Miwa
Junji Yuda
Shoji Miwa