Title:
新規の治療タンパク質ベースの分子クラス
Document Type and Number:
Japanese Patent JP4764881
Kind Code:
B2
Abstract:
The present invention provides new compositions and methods for preventing and treating pathogen infection. In particular, the present invention provides compounds having an anchoring domain that anchors the compound to the surface of a target cell, and a therapeutic domain that can act extracellularly to prevent infection of a target cell by a pathogen, such as a virus. The present invention also comprises therapeutic compositions having sialidase activity, including protein-based compounds having sialidase catalytic domains. Compounds of the invention can be used for treating or preventing pathogen infection, and for treating and reducing allergic and inflammatory responses. The invention also provides compositions and methods for enhancing transduction of target cells by recombinant viruses. Such compositions and methods can be used in gene therapy.
Inventors:
Fan
MALAKHOV,Michael
MALAKHOV,Michael
Application Number:
JP2007531167A
Publication Date:
September 07, 2011
Filing Date:
July 21, 2005
Export Citation:
Assignee:
Fan
International Classes:
C12N15/09; A61K9/06; A61K9/08; A61K9/10; A61K35/76; A61K38/43; A61P27/16; A61P31/16; A61P43/00; C07H21/04; C07K14/47; C07K19/00; C12N1/21; C12N9/24; C12N9/36; C12N15/74; A61K39/00
Domestic Patent References:
| JPS6420094A | 1989-01-24 |
Foreign References:
| WO2004047735A2 | 2004-06-10 |
Attorney, Agent or Firm:
Mieko Kashihara