Title:
窒素含有三環式化合物及び医薬品におけるその使用
Document Type and Number:
Japanese Patent JP7237078
Kind Code:
B2
Abstract:
Nitrogenous tricyclic compounds and uses thereof in medicine, in particular, a novel nitrogenous tricyclic compound used as an FXR active regulator and a stereoisomer, a geometrical isomer, a tautomer, a N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, and use of the compound in the manufacture of a drug for treating a disease and/or disorder regulated by FXR. A pharmaceutically acceptable composition containing the compound and a method of treating a disease and/or disorder mediated by FXR comprising administering the compound or pharmaceutical composition thereof.
Inventors:
Shine Yang
Xiao Jun Wan
Junwen Wu
Hong Cheng
Shen Tian Khao
Injun Jean
Xiao Jun Wan
Junwen Wu
Hong Cheng
Shen Tian Khao
Injun Jean
Application Number:
JP2020541888A
Publication Date:
March 10, 2023
Filing Date:
January 28, 2019
Export Citation:
Assignee:
SUNSHINE LAKE PHARMA CO.,LTD.
International Classes:
C07D491/044; A61K31/4353; A61P1/16; A61P3/04; A61P3/06; A61P3/10; A61P7/06; A61P9/04; A61P9/08; A61P9/10; A61P9/12; A61P15/10; A61P27/02; A61P29/00; A61P35/00
Domestic Patent References:
| JP2014500318A |
Foreign References:
| WO2016127924A1 |
Attorney, Agent or Firm:
Murayama Yasuhiko
Shinya Mihiro
Tatsuhiko Abe
Shinya Mihiro
Tatsuhiko Abe
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