Title:
非線形光学顕微鏡を用いた血管内脂質の非破壊的病理的変化診断プログラム
Document Type and Number:
Japanese Patent JP5444457
Kind Code:
B2
Abstract:
Disclosed is a system for diagnosing the pathological change in lipids in blood vessels using coherent anti-strokes raman microscopy which can image lipids abnormally deposited on the deep intima of blood vessels and analyze the components of the imaged lipids, without labeling or destroying blood vessels, to diagnose minute pathological changes in the blood vessels, whereby the stage of progression of lipid-related diseases can be determined.
Inventors:
Kim sepha
Lijayon
Lawnson
Mundaewon
Lijayon
Lawnson
Mundaewon
Application Number:
JP2012510724A
Publication Date:
March 19, 2014
Filing Date:
May 11, 2009
Export Citation:
Assignee:
KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE
International Classes:
G01N21/65; G02B21/00
Domestic Patent References:
| JP2009047435A | ||||
| JP2008249945A | ||||
| JP63009828A | ||||
| JP2008502408A |
Other References:
Haifeng Wang et al.,Coherent Anti-Stokes Raman Scattering Imaging of Axonal Myelin in Live Spinal Tissues,Biophysical Journal,2005年,Vol.89,pp.581-591
Ji-xin Cheng et al.,Multiplex Coherent Anti-Stokes Raman Scattering Microspectroscopy and Study of Lipid Vesicles,J.Phys.Chem.B,2002年,Vol.106,pp.8493-8498
Ji-xin Cheng et al.,Multiplex Coherent Anti-Stokes Raman Scattering Microspectroscopy and Study of Lipid Vesicles,J.Phys.Chem.B,2002年,Vol.106,pp.8493-8498
Attorney, Agent or Firm:
Shingo Sagawa
Motoko Kobayashi
Kiyotaka Kanamaru
Takahashi Shiori
Yosuke Kawano
Motoko Kobayashi
Kiyotaka Kanamaru
Takahashi Shiori
Yosuke Kawano