NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR TREATMENT OF DISEASES

Title:

NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR TREATMENT OF DISEASES

Document Type and Number:

Japanese Patent JP2016164159

Kind Code:

A

Abstract:

PROBLEM TO BE SOLVED: To provide compounds that are novel modulators, e.g., activators or agonists, of the human calcium sensing receptor (CaSR) and effective in treatment of chronic kidney disease and osteoporosis.SOLUTION: The invention provides a compound represented by the formula I or a pharmaceutically acceptable salt, solvate or in vivo hydrolyzable ester thereof, e.g., a compound of the formula (II) or the like.SELECTED DRAWING: Figure 2

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Inventors:

JEF FENSHOLDT
SOPHIE ELISABETH HAVEZ
BJARNE NOERREMARK

Application Number:

JP2016043790A

Publication Date:

September 08, 2016

Filing Date:

March 07, 2016

Export Citation:

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Assignee:

LEO PHARMA AS

International Classes:

A61K31/136; C07C211/42; A61K31/155; A61K31/16; A61K31/164; A61K31/165; A61K31/18; A61K31/192; A61K31/198; A61K31/24; A61K31/275; A61K31/341; A61K31/343; A61K31/357; A61K31/381; A61K31/397; A61K31/40; A61K31/404; A61K31/4152; A61K31/4164; A61K31/4245; A61K31/427; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4439; A61K31/445; A61K31/495; A61K31/5375; A61K31/592; A61K31/593; A61K31/663; A61P1/00; A61P3/14; A61P5/22; A61P9/00; A61P13/12; A61P19/08; A61P19/10; A61P25/00; A61P25/28; A61P35/00; A61P43/00; C07C211/53; C07C229/48; C07C237/24; C07C255/29; C07C255/58; C07C257/18; C07C259/08; C07C259/18; C07C309/15; C07C311/51; C07D205/04; C07D205/08; C07D207/08; C07D207/16; C07D209/18; C07D211/46; C07D211/66; C07D213/30; C07D213/38; C07D213/53; C07D213/80; C07D231/40; C07D233/60; C07D265/30; C07D271/06; C07D295/104; C07D295/13; C07D307/12; C07D307/56; C07D307/58; C07D307/81; C07D319/18; C07D333/38; C07D333/40; C07D413/06; C07D417/06

Foreign References:

US6211244B1	2001-04-03
WO2010021351A1	2010-02-25
WO2000076973A1	2000-12-21
WO2007059230A2	2007-05-24
WO2006110683A1	2006-10-19
WO2006066779A1	2006-06-29

Attorney, Agent or Firm:

Takuji Yamada
Aoyama Aoi
Michiko Matsutani
Sakurai Yoko

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