Title:
NOVEL GLYCOCONJUGATE, GLYCOAMINO ACID, INTERMEDIATES THERETO, AND USES THEREOF
Document Type and Number:
Japanese Patent JP2012132025
Kind Code:
A
Abstract:
To provide novel constructs capable of eliciting a more sustained or effective, and preferably selective immune response.
The present invention provides novel n-alkenyl glycosides and glycoconjugates, n-alkyl glycoamino acids, and methods for the synthesis thereof. The present invention further provides novel clustered glycopeptides and methods for the synthesis thereof. The present invention provides methods for the treatment of cancer, preferably for the prevention of recurrence of cancer, and methods for inducing antibodies in a subject, comprising administering to a subject in need, an effective amount of any of the inventive glycoconjugates as disclosed herein.
Inventors:
DANISHEFSKY SAMUEL J
ALLEN JENNIFER R
RAGUPATHI GOVINDASWAMI
LIVINGSTON PHILIP O
WILLIAMS LAWRENCE
ALLEN JENNIFER R
RAGUPATHI GOVINDASWAMI
LIVINGSTON PHILIP O
WILLIAMS LAWRENCE
Application Number:
JP2012076266A
Publication Date:
July 12, 2012
Filing Date:
March 29, 2012
Export Citation:
Assignee:
SLOAN KETTERING INST CANCER
International Classes:
C08B37/00; A61K31/715; A61K38/00; A61K39/00; A61K39/39; A61K45/00; A61K47/48; A61P35/00; A61P35/04; C07H15/04; C07H15/10; C07H15/18; C07K1/107; C07K5/062; C07K9/00; C07K14/435
Domestic Patent References:
| JPH1135594A | 1999-02-09 | |||
| JPS5576894A | 1980-06-10 |
Foreign References:
| WO1998046246A1 | 1998-10-22 | |||
| DE19802748A1 | 1999-07-29 |
Other References:
JPN5002011586; ＲＡＧＵＰＡＴＨＩ，ＧＯＶＩＮＤＡＳＷＡＭＩ: ＡＮＧＥＷ．ＣＨＥＭ． Ｖ３６ Ｎ１／２, 1997, Ｐ１２５-１２８, ＩＮＴ．ＥＤ．ＥＮＧＬ．
JPN6011001876; ＰＮＡＳ ９６, 19990511, ５７１０-５７１５
JPN6011001877; Ｊ． Ａｍ． Ｃｈｅｍ． Ｓｏｃ． １１８, 1996, １１４８８-１１５００
JPN6011001878; Ａｎｇｅｗ． Ｃｈｅｍ． Ｉｎｔ． Ｅｄ． ｖ３８，ｎ４, 19990215, ５６３-５６６
JPN6011001876; ＰＮＡＳ ９６, 19990511, ５７１０-５７１５
JPN6011001877; Ｊ． Ａｍ． Ｃｈｅｍ． Ｓｏｃ． １１８, 1996, １１４８８-１１５００
JPN6011001878; Ａｎｇｅｗ． Ｃｈｅｍ． Ｉｎｔ． Ｅｄ． ｖ３８，ｎ４, 19990215, ５６３-５６６
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro