Title:
NOVEL SUBSTITUTED DIHYDROPYRIDINE DERIVATIVE, ITS PRODUCTION, DRUG COMPOSED OF SAID DERIVATIVE AND ITS PRODUCTION
Document Type and Number:
Japanese Patent JPS63119464
Kind Code:
A
Abstract:
The invention relates to new substituted dihydropyridine derivatives of the general formula (I), wherein R1 and R6 are as defined herein after, the racemic and optically active variants as well as mixtures thereof, furthermore the acid addition salts of these compounds, pharmaceutical compositions containing the same and a process for the preparation thereof. The compounds of the general formula (I) can be advantageously applied for the treatment of pathologically severe hypertensions, their toxicity is low and they possess an advantageous therapeutic index.
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Inventors:
GEEZA SHIRAAJII
EEBUA BOZOO
RAASUROO TSUORUNERU
RAASUROO YASURITSU
JIYORUJI RABUROTSUKII
YOOJIEFU BORUSHI
ISHIYUTOBUAAN EREKESHIYU
JIYOENJII NAJII NEEE CHIYOKAAS
ANDORAASHIYU BUARUROO
ZUZA RAANGU NEEE RIIMERU
JIYORUJII CHIEE
JIYURA HORUBUAATO
IRONA BOODEI
EEBUA BOZOO
RAASUROO TSUORUNERU
RAASUROO YASURITSU
JIYORUJI RABUROTSUKII
YOOJIEFU BORUSHI
ISHIYUTOBUAAN EREKESHIYU
JIYOENJII NAJII NEEE CHIYOKAAS
ANDORAASHIYU BUARUROO
ZUZA RAANGU NEEE RIIMERU
JIYORUJII CHIEE
JIYURA HORUBUAATO
IRONA BOODEI
Application Number:
JP22997087A
Publication Date:
May 24, 1988
Filing Date:
September 16, 1987
Export Citation:
Assignee:
ALKALOIDA VEGYESZETI GYAR
International Classes:
A61K31/445; A61K31/451; A61K31/455; A61P3/00; A61P9/10; A61P9/12; C07D211/90; C07D401/12; C07D405/12; (IPC1-7): A61K31/445; A61K31/455; C07D211/90
Attorney, Agent or Firm:
Soichi Takezawa