Title:
オリゴヌクレオチドの分離及び脱保護方法
Document Type and Number:
Japanese Patent JP2006501250
Kind Code:
A
Abstract:
Methods for deprotecting and derivatizing oligonucleotides that are non-covalently bound to a solid support are described. The methods include providing a plurality of oligonucleotides linked to one or more hydrophobic separation functions, wherein the plurality includes protected oligonucleotides, precipitating the plurality of oligonucleotides on a hydrophobic solid support using an organic solvent to produce non-covalently immobilized oligonucleotides, and deprotecting the immobilized oligonucleotides.
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Inventors:
Kwiatkowski, Marek
Application Number:
JP2004532510A
Publication Date:
January 12, 2006
Filing Date:
August 28, 2003
Export Citation:
Assignee:
Kiatec Activola Get
International Classes:
C07H1/06; C07H21/00; C12N15/09; C07H21/02; C07H21/04
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Naganuma Akio
Isoyama Asami
Hajime Asamura
Naganuma Akio
Isoyama Asami