Title:
pH及びグルコースの光学的決定
Document Type and Number:
Japanese Patent JP5017377
Kind Code:
B2
Abstract:
Embodiments of the present invention are directed to an optical sensor capable of measuring two analytes simultaneously with a single indicator system. In preferred embodiments, the sensor comprises a fluorescent dye having acid and base forms that facilitate ratiometric pH sensing, wherein the dye is further associated with a glucose binding moiety and configured to generate a signal that varies in intensity with the concentration of glucose.
Inventors:
Merkle, David Earl.
Pickpocket, Jeff Tee.
Wesling, Ritchie A.
Romei, Matthew A.
Pickpocket, Jeff Tee.
Wesling, Ritchie A.
Romei, Matthew A.
Application Number:
JP2009549167A
Publication Date:
September 05, 2012
Filing Date:
January 28, 2008
Export Citation:
Assignee:
Gourmet Trix, Incorporated
International Classes:
G01N21/78; C09K11/06; G01N21/64; G01N33/66; G01N33/84
Domestic Patent References:
| JP2002523774A | ||||
| JP2004536279A | ||||
| JP2010517693A |
Foreign References:
| WO2006023725A2 | ||||
| WO2005065241A2 |
Other References:
BADUGU R,TALANTA,NL,ELSEVIER,2005年 4月30日,V66 N3,P569-574
CAPPUCCIO FRANK E,JOURNAL OF FLUORESCENCE,2004年 9月,V14 N5,P521-533
GAMSEY SOYA,LANGMUIR,THE ACS JOURNAL OF SURFACES AND COLLOIDS,2006年10月10日,V22 N21,P9067-9074
CAPPUCCIO FRANK E,JOURNAL OF FLUORESCENCE,2004年 9月,V14 N5,P521-533
GAMSEY SOYA,LANGMUIR,THE ACS JOURNAL OF SURFACES AND COLLOIDS,2006年10月10日,V22 N21,P9067-9074
Attorney, Agent or Firm:
Yoshiyuki Kawaguchi
Hidemi Matsukura
Mayuko Wakuda
Tsutomu Toyama
Shinichi Sanuki
Takeshi Niwa
Hidemi Matsukura
Mayuko Wakuda
Tsutomu Toyama
Shinichi Sanuki
Takeshi Niwa