OPTICALLY ACTIVE α-ALKYLFLUORO-, TRIFLUOROMETHYL- OR TRIFLUOROMETHOXY-SUBSTITUTED BENZYL ALCOHOL AND METHOD FOR PRODUCING THE SAME

Title:

OPTICALLY ACTIVE α-ALKYLFLUORO-, TRIFLUOROMETHYL- OR TRIFLUOROMETHOXY-SUBSTITUTED BENZYL ALCOHOL AND METHOD FOR PRODUCING THE SAME

Document Type and Number:

Japanese Patent JP2003226659

Kind Code:

A

Abstract:

To provide a new optically active α-alkylfluoro-, trifluoromethyl- or trifluoromethoxy-substituted benzyl alcohol which is an important intermediate for medicines and agrochemicals, and to provide a means capable of efficiently producing the compound.

The optically active α-alkylfluoro-, trifluoromethyl- or trifluoromethoxy-substituted benzyl alcohol is efficiently produced by asymmetrically alkylating a fluoro-, trifluoromethyl- or trifluoromethoxy-substituted benzaldehyde with a dialkyl zinc in the presence of an asymmetric catalyst prepared from optically active taddoles and tetraisopropoxytitanium.

More Like This:

JP2002069020	METHOD FOR PRODUCING FLUOROALCOHOL
WO/1993/016022	PALLADIUM CATALYZED ALKYLATIVE CYCLIZATION USEFUL IN SYNTHESIS OF VITAMIN D AND ANALOGUES

Inventors:

KANAI MASATOMI
ISHII AKIHISA
KURIYAMA KATSU
YASUMOTO MANABU
INOMIYA NORITO
OTSUKA TAKASHI
UEDA KOJI

Application Number:

JP2002287377A

Publication Date:

August 12, 2003

Filing Date:

September 30, 2002

Export Citation:

Click for automatic bibliography generation Help

Assignee:

CENTRAL GLASS CO LTD

International Classes:

C07C29/44; C07B53/00; C07B61/00; C07C33/46; C07C41/30; C07C43/225; (IPC1-7): C07C29/44; C07C33/46; C07C41/30; C07C43/225

Attorney, Agent or Firm:

Yoshiyuki Nishi

Previous Patent: PASTE AND EXTERNAL CATAPLASM USING THE SAME

Next Patent: METHOD FOR PRODUCING BISPHENOLS