Title:
アセトアルデヒド毒性を低減するためのβ－エスシンを含有する経口組成物
Document Type and Number:
Japanese Patent JP7070933
Kind Code:
B2
Abstract:
The present invention relates to an oral liquid composition comprising β-escin (beta-escin) and chokeberry fruit extract for use in treatment and prevention of conditions related to the increased acetaldehyde toxicity, such as veisalgia, alcohol poisoning, esophageal cancer, oropharyngolaryngeal cancer or a condition resulting from insufficient aldehyde dehydrogenase (ALDH) enzyme activity. Administration of the composition of the invention to a subject results in an increased metabolism of aldehydic substrates, in particular those originating from catabolism of alcohol and representing a hazard to humans due to their toxicity.
Inventors:
Koziak, Catharzina
Application Number:
JP2019528118A
Publication Date:
May 18, 2022
Filing Date:
November 24, 2017
Export Citation:
Assignee:
Essilab Espe Zo O.
International Classes:
A61K9/08; A61K31/704; A61K47/46; A61P39/02
Domestic Patent References:
| JP7053385A |
Foreign References:
| KR1020140090453A |
Attorney, Agent or Firm:
Ryoichi Takaoka
Nao Oda
Akiyo Iwahori
Kamoto Takahashi
Nao Oda
Akiyo Iwahori
Kamoto Takahashi