Title:
軟骨再生剤としてアピゲニンを含有する骨関節炎治療組成物
Document Type and Number:
Japanese Patent JP2007508371
Kind Code:
A
Abstract:
Disclosed is a novel use of apigenin as a chondroregenerative agent, which has the effects of reducing elevated of cartilage destruction markers including total synovial fluid volume and proteoglycan, total proteins and prostaglandin in a synovial fluid, improving the condition of synovial cells, and regenerating cartilage. Also, the present invention discloses a therapeutic agent for osteoarthritis comprising apigenin as an agent regenerating articular cartilage, and a method of treating osteoarthritis using such a therapeutic agent.
Inventors:
Chang Sing Parc
Joo Hook Kang
Kyung Mi Kim
Joo Hook Kang
Kyung Mi Kim
Application Number:
JP2006535271A
Publication Date:
April 05, 2007
Filing Date:
October 15, 2004
Export Citation:
Assignee:
KMS Corporation Limited
Sung-Yeown Huwang
Sung-One wang
Sung-Yeown Huwang
Sung-One wang
International Classes:
A61K31/352; A23L1/30; A61K9/06; A61K9/08; A61P11/02; A61P11/08; A61P19/02; A61P29/00; A61P43/00; C07D311/30
Domestic Patent References:
| JPH0725761A | 1995-01-27 |
Attorney, Agent or Firm:
Toru Ishikawa