CD23に結合するペプチドおよびペプチド模倣体

Japanese Patent JP2007531536

A

The present invention describes compounds comprising new and useful peptides and peptidomimetics that can bind to CD23. They are capable of reducing inflammatory responses associated with auto-immune diseases, chronic inflammatory diseases, allergies and other inflammatory conditions such as those mediated by the mammalian immune system. Compounds of the present invention relate to a CD23-binding peptide wherein said peptide comprises an amino-acid sequence of X1—X2—X3—X4—X5—X6—X7—X8, wherein: X1 is Phe, or is absent; X2 is His or Ala; X3 is Glu, Ser, Ala, Asn, Lys, or Cys; X4 is Asn, Phe, Gln, Pro, Ser, or Ala; X5 is Trp; X6 is Pro, Arg, Glu, Gly, Cys, or Lys; X7 is Ser, Pro, Leu, Thr Ala, Gly, Asn, or absent; and X8 is Phe, Gly, or is absent.

Mossaray, Mohammad Dhavad
Moinette, daniel
Vinsendo, philippe
Lambert, Jerome
Self, Christopher Earl

JP2007506867A

November 08, 2007

April 05, 2005

Click for automatic bibliography generation  

Universite Bordeaux 2

C12N15/09; A01H5/00; A01K67/027; A61K38/00; A61K38/08; A61P1/04; A61P1/18; A61P3/08; A61P3/10; A61P5/14; A61P5/48; A61P11/00; A61P11/02; A61P11/04; A61P11/06; A61P13/12; A61P15/00; A61P17/02; A61P17/04; A61P17/06; A61P19/02; A61P25/00; A61P25/16; A61P27/02; A61P29/00; A61P35/00; A61P35/02; A61P37/00; A61P37/06; A61P37/08; A61P43/00; C07K7/06; C07K7/08; C07K14/00; C07K14/47; C07K14/705; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/02; C12Q1/02; G01N33/53; G01N33/532

JP2002187899A	2002-07-05
JP2004509846A	2004-04-02

WO2003097091A2	2003-11-27
WO2002028888A2	2002-04-11

Kazuo Shamoto
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Reiko Izumiya

Previous Patent: ニトリルヒドラターゼ−生成菌株ロドコッカス属ロドクロウスＭ３３の培�...

Next Patent: アポリポタンパク質Ａ−Ｉおよびアポリポタンパク質Ａ−ＩＭＩＬＡＮＯ�...