Title:
PERCUTANEOUSLY ABSORBABLE PLASTER
Document Type and Number:
Japanese Patent JP3251108
Kind Code:
B2
Abstract:
PURPOSE: To provide a percutaneously absorbable plaster excellent in adhesivity and not giving irritation to skins and also pain to the skins when peeled.
CONSTITUTION: An self-adhesive layer comprising 100 pts.wt. of a self-adhesive agent, 10-40 pts.wt. of a medicinal substance (e.g. 17-β-estradiol), if necessary, furthermore a tackifying resin and a percutaneous absorption-accelerating agent is laminated to one side of a support. The self-adhesive agent comprises 5-20 pts.wt. of a polyvinyl pyrrolidone having a mol.wt. of 1000000-5000000 and 100 pts.wt. of either of a silicone adhesive and an acrylic adhesive agent comprising the acrylic copolymer of one or more methacrylate compounds selected from dodecyl methacrylate and octyl methacrylate with one or more acrylate compounds selected from dodecyl acrylate and octyl acrylate. The medicinal substance is contained in the self-adhesive agent in a supersaturated state exceeding the solubility of the self-adhesive agent, and the supersaturated state can stably be maintained for a long period.
Inventors:
Hiroshi Kuroda
Application Number:
JP24675293A
Publication Date:
January 28, 2002
Filing Date:
October 01, 1993
Export Citation:
Assignee:
Sekisui Chemical Co.,Ltd.
International Classes:
A61K9/70; A61K47/32; A61K47/36; A61K47/38; A61K47/42; (IPC1-7): A61K9/70; A61K47/32; A61K47/36; A61K47/38; A61K47/42
Domestic Patent References:
| JP334923A |