Title:
ペリオスチン抗体およびその使用方法
Document Type and Number:
Japanese Patent JP2021518387
Kind Code:
A
Abstract:
本発明者らは、ヒトペリオスチンタンパク質上のがん特異的グリカン（炭水化物）改変を認識する抗原結合試薬および抗原結合コンジュゲートを開発した。Ｍｇａｔ３遺伝子が増幅しているがんを特異的に処置するための、これらの組成物を使用する様々なｉｎ ｖｉｔｒｏおよびｉｎ ｖｉｖｏでの診断および／または治療方法も本明細書に開示される。
Inventors:
Abbott Karen
Shera-Natalie
Shera-Natalie
Application Number:
JP2020550607A
Publication Date:
August 02, 2021
Filing Date:
March 19, 2019
Export Citation:
Assignee:
Bio Ventures Limited Liability Company
International Classes:
C07K16/18; A61K35/12; A61K35/17; A61K39/395; A61K45/00; A61K47/68; A61K49/16; A61K49/22; A61K51/10; A61P1/04; A61P11/00; A61P13/12; A61P15/00; A61P25/00; A61P35/00; A61P43/00; C12N5/10
Foreign References:
| US20110033875A1 | 2011-02-10 | |||
| WO2016057890A1 | 2016-04-14 | |||
| US20140154710A1 | 2014-06-05 |
Other References:
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SIEGEL RW. ET AL.: "High efficiency recovery and epitope-specific sorting of an scFv yeast display library", J IMMUNOL METHODS, vol. 286, JPN6023015652, 2004, pages 141 - 53, XP004503454, ISSN: 0005041666, DOI: 10.1016/j.jim.2004.01.005
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SIEGEL RW. ET AL.: "High efficiency recovery and epitope-specific sorting of an scFv yeast display library", J IMMUNOL METHODS, vol. 286, JPN6023015652, 2004, pages 141 - 53, XP004503454, ISSN: 0005041666, DOI: 10.1016/j.jim.2004.01.005
ZHAO A. ET AL.: "Rapid isolation of high-affinity human antibodies against the tumor vascular marker Endosialin/TEM1,", J IMMUNOL METHODS, vol. 363, JPN6023015648, 2011, pages 221 - 32, XP002770836, ISSN: 0005041667, DOI: 10.1016/j.jim.2010.09.001
Attorney, Agent or Firm:
Shinichiro Tanaka
▲吉▼田 和彦
Hiroyuki Suda
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Shimura
▲吉▼田 和彦
Hiroyuki Suda
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Shimura