Title:
PHARMACEUTICAL PREPARATION IN SOLID RETARDING FORM
Document Type and Number:
Japanese Patent JPH05194197
Kind Code:
A
Abstract:
PURPOSE: To prepare a sustained release formulation of a solid pharmaceutical preparation by an extruding and continuous forming method for allowing the treatment to successively progress with a high throughput when the material loss is slight. CONSTITUTION: A sustained release formulation is prepared by melt-extruding a mixture of an active ingredient of a pharmaceutical preparation with a polymer melt comprising (a) a water-insoluble poly(meth)acrylate, (b) a water-soluble hydroxyalkyl cellulose having 2-3 carbon atoms in the hydroxyalkyl group or hydroxyalkylmethyl cellulose, or a N-vinylpyrrolidone polymer having vinyl acetate, or a mixture of preceding two, (c) one or more conventional pharmaceutical auxiliaries, and successively forming the molten mixture.
Inventors:
BUINFURIITO MIYURAA
RAINHARUTO SHIYUPENGURAA
SUBUEN GURABOFUSUKII
AKUSERU ZANNAA
RAINHARUTO SHIYUPENGURAA
SUBUEN GURABOFUSUKII
AKUSERU ZANNAA
Application Number:
JP31006092A
Publication Date:
August 03, 1993
Filing Date:
November 19, 1992
Export Citation:
Assignee:
BASF AG
International Classes:
A61K9/20; A61K9/22; (IPC1-7): A61K9/22
Attorney, Agent or Firm:
Toshio Yano (2 outside)