Title:
ピペリジン誘導体、これの製造方法及びこれを含む痴呆治療用薬学的組成物
Document Type and Number:
Japanese Patent JP4179468
Kind Code:
B2
Abstract:
The present invention relates to novel piperidine derivatives having effect of inhibiting acetylcholinesterase and aggregation of beta-amyloid, Alzheimer's disease-induced protein, and treatment for Alzheimer's disease containing the same, the piperidine derivatives represented by Formula 3.
Inventors:
Kwon Young Yi
Kang Zhong Ho
Reference
Lisanze
Kind one
Rikanfun
Han Sung Il
Yoon Yoo Sung
Kang Zhong Ho
Reference
Lisanze
Kind one
Rikanfun
Han Sung Il
Yoon Yoo Sung
Application Number:
JP2003536229A
Publication Date:
November 12, 2008
Filing Date:
October 16, 2002
Export Citation:
Assignee:
Esteey Nara Company Limited
International Classes:
C07D211/44; C07D211/46; A61K31/445; A61K31/453; A61P25/28; C07D401/12
Domestic Patent References:
| JP7109275A | ||||
| JP2000501117A | ||||
| JP2001139547A | ||||
| JP62005956A | ||||
| JP2005529840A |
Other References:
Doody R.S.,Clinical ,European Neuropsychopharmacology ,1999年,9,S69-S77,supplement 2,
Zhao等,Synthesis of 1,2-Diamino and 1,2-Aminoalcohol Derivatives in the Piperidine and Pyrrolidine Series as Anti-amnesic Agents,Biooganic and Medicinal Chemistry,1999年,7(8),1647-1654
Zhao等,Synthesis of 1,2-Diamino and 1,2-Aminoalcohol Derivatives in the Piperidine and Pyrrolidine Series as Anti-amnesic Agents,Biooganic and Medicinal Chemistry,1999年,7(8),1647-1654
Attorney, Agent or Firm:
Sakuo Yamaguchi