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Title:
POLARIZED 129XE CONTRAST AGENT FOR IN VIVO EVALUATION OF RESPIRATORY ORGAN DISORDER OR CARDIOPULMONARY DISORDER SUCH AS CHRONIC HEART FAILURE
Document Type and Number:
Japanese Patent JP2009106788
Kind Code:
A
Abstract:

To provide a method for screening and/or diagnosing respiratory disorder or disease, cardiopulmonary disorder or disease such as chronic heart failure, and/or a method for monitoring efficacy of therapeutics administered to a subject to treat the disorder or disease.

Dynamic data sets of an NMR spectroscopy signal of polarized 129Xe are obtained in a selected structure, environment, or system. The signal data can be used to evaluate: (a) the physiology of a membrane or tissue; (b) the operational condition or function of a body system or the portion thereof (when at rest or under stimulation); and/or (c) the efficacy of a therapeutic treatment used to treat a diagnosed disorder, disease, or condition.


Inventors:
DRIEHUYS BASTIAAN
HALL MARGARET
MARELLI CLAUDIO
Application Number:
JP2009013031A
Publication Date:
May 21, 2009
Filing Date:
January 23, 2009
Export Citation:
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Assignee:
MEDI PHYSICS INC
International Classes:
A61B5/055; A61B5/08; A61B10/00; G01N24/08; G01N24/12; G01R33/28; A61B5/0275
Foreign References:
WO2001067955A22001-09-20
US20010000727A12001-05-03
Attorney, Agent or Firm:
Kenichi Matsumoto
Hirokazu Ogura
Toshihisa Kurokawa