Title:
標的ポリペプチドを提示するためのポリペプチド担体及びその使用
Document Type and Number:
Japanese Patent JP6863966
Kind Code:
B2
Abstract:
The invention relates to a polypeptide carrier for presenting a target polypeptide, and use thereof. In particular, the invention relates to a nucleic acid molecule, comprising a nucleotide sequence encoding a polypeptide carrier, and being used for insertion of a nucleotide sequence encoding a target polypeptide. In addition, the invention further relates to a recombinant protein comprising the polypeptide carrier and a target polypeptide. Furthermore, the invention further relates to use of the nucleic acid molecule and the recombinant protein. In addition, the invention further relates to a vaccine or a pharmaceutical composition useful for preventing, alleviating or treating HBV infection or a disease associated with HBV infection (e.g., hepatitis B), comprising a recombinant protein comprising the polypeptide carrier of the invention and an epitope from HBV.
Inventors:
Chan, Tian Inn
Ewan, Kwan
Guo, Shwelan
Chang, Inn
Zao, Kin Chan
Chan, Chun
Shah, Nin Xiao
Ewan, Kwan
Guo, Shwelan
Chang, Inn
Zao, Kin Chan
Chan, Chun
Shah, Nin Xiao
Application Number:
JP2018510399A
Publication Date:
April 21, 2021
Filing Date:
August 24, 2016
Export Citation:
Assignee:
Shaamen University
Yang Shen Tan Company, Limited
Yang Shen Tan Company, Limited
International Classes:
C12N15/36; A61K35/76; A61K39/00; A61K39/29; A61K47/64; A61K47/65; A61P31/20; A61P35/00; A61P37/04; C07K14/02; C07K14/47; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N7/01; C12N15/12; C12N15/62; C12P21/02
Other References:
Journal of Biotechnology,1996年,vol.44,p.91-96
PNAS,2013年,vol.110,no.40,p.16151-16156
Journal of Virology,1992年,vol.66,no.1,p.106-114
PNAS,2013年,vol.110,no.40,p.16151-16156
Journal of Virology,1992年,vol.66,no.1,p.106-114
Attorney, Agent or Firm:
Asamura patent office