Title:
分子相互作用ネットワークの予測方法
Document Type and Number:
Japanese Patent JP2005503535
Kind Code:
A
Abstract:
The present invention relates to a method for identifying unknown molecular interactions within biological networks based on representations of molecules as sets of conserved features. Such molecules include but are not limited to proteins and nucleic acid molecules which can be represented as collections of conserved features, such as domains and motifs in proteins. The method of the invention comprises computing the attraction probabilities between molecules followed by calculation of the probability of a biological network. The method of the invention can be applied across species, where interaction data from one, or several species, can be used to infer molecular interactions between molecules within or between organisms. The method of the present invention may be used to identify molecular interactions which can serve as drug screening targets.
Inventors:
Ruzetsky, Andrei
Ro, Shaw-Whoi
Gomez, Shaun, M.
Ro, Shaw-Whoi
Gomez, Shaun, M.
Application Number:
JP2002564586A
Publication Date:
February 03, 2005
Filing Date:
February 11, 2002
Export Citation:
Assignee:
The Trustees of Columbia University Inn The City of New York
International Classes:
G01N33/48; G16B5/20; C12Q1/00; C12Q1/68; C40B30/02; G01N33/53; G06F17/18; G06G7/48; G06G7/58; G16B35/20; (IPC1-7): G01N33/48
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Ishii Teiji
Satoshi Fujita
Ishii Teiji