Title:
単球介在性疾患を治療するための組成物の調製
Document Type and Number:
Japanese Patent JP5175723
Kind Code:
B2
Abstract:
The invention relates to a method of treating or diagnosing a disease state mediated by monocytes. The method utilizes a composition comprising a conjugate or complex of the general formula Ab-X wherein the group Ab comprises a ligand that binds to monocytes, and when the conjugate is being used for treatment of the disease state, the group X comprises an immunogen, a cytotoxin, or a compound capable of altering monocyte function, and when the conjugate is being used for diagnosing the disease state, the group X comprises an imaging agent.
Inventors:
Rho, Philip, Stewart
Hill Jen Brink, Andrew, Richard
Hill Jen Brink, Andrew, Richard
Application Number:
JP2008519744A
Publication Date:
April 03, 2013
Filing Date:
July 05, 2006
Export Citation:
Assignee:
PURDUE RESEARCH FOUNDATION
International Classes:
A61K31/519; A61K9/127; A61K31/196; A61K31/405; A61K31/573; A61K47/48; A61P13/12; A61P19/02; A61P29/00; A61P37/00
Domestic Patent References:
| JP2004530678A |
Foreign References:
| WO2004100983A2 |
Other References:
Arthritis Rheum.,1999年,Vol.42, No.8,1609-1616
Attorney, Agent or Firm:
Isshiki International Patent Service Corporation