PREPARATION OF ISOQUINOLINE COMPOUND - CHINOIN GYOGYSZER ES VEGYESZET

Title:

PREPARATION OF ISOQUINOLINE COMPOUND

Document Type and Number:

Japanese Patent JPH0570461

Kind Code:

A

Abstract:

PURPOSE: To provide a producing method of high purity 1-(3',4'-diethoxy- benzyl)-6,7-diethoxy-3,4-dihydro-isoquinoliniumtheophylline-7-acetate.

CONSTITUTION: In this producing method, 1-(3',4'-diethoxy-benzyl)-6,7-diethoxy-3,4- dihydro-isoquinoline is allowed to react with theophylline-7-acetic acid in the presence of water and one or more kinds of org. solvents to produce 1-(3',4'- diethoxy-benzyl)-6,7-diethoxy-3,4-dihydro-isoquinolinium-theophylline-7-acetate monohydrate. The obtd. compd. is dehydrated to obtain 1-(3',4'-dithoxy- benzyl)-6,7-diethoxy-3,4-dihydro-isoquinolinium-theophylline-7-acetate of about 99.5% purity.

Inventors:

ANTARU FURIESUZU
ZUSUZUSANNA NATSUDO
RAYOSU NAGII
TAMASU KAREI

Application Number:

JP3204992A

Publication Date:

March 23, 1993

Filing Date:

February 19, 1992

Export Citation:

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Assignee:

CHINOIN GYOGYSZER ES VEGYESZET

International Classes:

C07D217/20; C07D473/08; C07D217/10; (IPC1-7): C07D217/20; C07D473/08

Attorney, Agent or Firm:

Akira Asamura (2 outside)

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