To obtain the subject medicine capable of preventing and treating cataract, comprising a furanone derivative.
This medicine comprises a furanone derivative of the formula (R1 to R3 are each H, hydroxyl, amino, a halogen, mercapto, carboxyl, carbamoyl, an alkyl, an alkenyl, an aryl, etc.; R4 is H, amino, a halogen, carboxyl, an alkyl, an aryl, an aralkyl, etc.) or its salt as an active ingredient. 2.5-Dimethyl-4-pivaloyloxy-3H(2H)-furanone is preferable as the compound of the formula. A dose is 0.01-1,000mg/time/day/adult in the case of injection. In the case of an internal medicine, the medicine is administered several times per adult daily and a dose is 0.1-1,000mg/time. In the case of an eye drop, one to two drops of 0.01-10% solution are applied once to five times a day drop. Senile cataract based on oxidation disorder can be prevented and treated by instillation or administration.
| WO/2008/040097 | FURANONE COMPOUNDS AND LACTAM ANALOGUES THEREOF |
| JPS58121214 | INHIBITOR OF BLOOD PLATELET AGGREGATION |
SASAKI TSUTOMU
ISHIKAWA HIROHARU
IWAI YUKIHIKO
MATSUDO TAKANAO
MORI KENJI
KIKUCHI MAMORU
SAITO MINORU
KASAI KOICHI
