Title:
PRIONLESS MYELOMA CELL AND APPLICATION THEREOF
Document Type and Number:
Japanese Patent JP2003219868
Kind Code:
A
Abstract:
To establish a myeloma cell line where the gene encoding prion protein is deleted, to produce an anti-prion monoclonal antibody-productive prionless hybridoma by using the myeloma cell line, to produce prion protein-free vaccines, and to detect abnormal prion proteins.
The prionless myeloma cell line where the gene encoding the prion protein is deleted is provided. A method for producing the myeloma cell line is also provided.
Inventors:
ITOHARA SHIGEMI
ONODERA SETSU
TSUKUI KAZUO
ONODERA SETSU
TSUKUI KAZUO
Application Number:
JP2002022499A
Publication Date:
August 05, 2003
Filing Date:
January 30, 2002
Export Citation:
Assignee:
RIKAGAKU KENKYUSHO
NIPPON SEKIJUJISHA
NIPPON SEKIJUJISHA
International Classes:
G01N33/48; A61K39/00; A61K39/12; A61K39/395; C12N5/10; C12N7/02; C12N15/09; C12Q1/02; (IPC1-7): C12N5/10; A61K39/00; A61K39/12; A61K39/395; C12N7/02; C12Q1/02; G01N33/48
Attorney, Agent or Firm:
Yusuke Hiraki (2 outside)
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