Title:
カリクレイン阻害剤のプロドラッグ
Document Type and Number:
Japanese Patent JP7128181
Kind Code:
B2
Abstract:
Disclosed are compounds of formula I, II, and III, and pharmaceutically acceptable salts thereof, which are inhibitors of kallikrein. Also provided are pharmaceutical compositions comprising such a compound, and methods involving use of the compounds and compositions in the treatment and prevention of acquired or hereditary angioedema, or other diseases and conditions characterized by aberrant kallikrein activity.
Inventors:
Kotian, Pravin Er
Bab, Yaragadda Es
Kumar, Vy Satish
Cintareddy, Venkat Earl
Zhang, Wafer
Voghetti, Lakshmi Narayana
Bab, Yaragadda Es
Kumar, Vy Satish
Cintareddy, Venkat Earl
Zhang, Wafer
Voghetti, Lakshmi Narayana
Application Number:
JP2019522794A
Publication Date:
August 30, 2022
Filing Date:
October 27, 2017
Export Citation:
Assignee:
BIOCRYST PHARMACEUTICALS,INC.
International Classes:
C07D213/81; A61K31/4418; A61K31/443; A61K31/4433; A61P7/02; A61P9/00; A61P43/00; C07D405/12
Domestic Patent References:
| JP2004523481A |
Foreign References:
| WO2016029214A1 |
Attorney, Agent or Firm:
Hiroshi Higuchi
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