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Title:
PRODUCTION OF 1,3-DIMETHYL-5-FLUORO-PYRAZOLE-4-CARBOXANILIDE
Document Type and Number:
Japanese Patent JPH09176126
Kind Code:
A
Abstract:

To produce a compound having fungicidal activity in high purity and yield without causing side reactions.

The objective compound of the formula I [Ar is a (substituted) phenyl] is produced by reacting 1,3-dimethyl-5-chloro-pyrazole-4-carbonyl chloride of the formula II with a fluoride and reacting the resultant 1,3-dimethyl-5- fluoropyrazole-4-carbonyl fluoride of the formula III with an aniline compound of the formula, H2N-Ar in the presence of an acid acceptor. The reaction of the compound of the formula II with the fluoride (e.g. potassium fluoride) is carried out in a solvent such as sulfolane at 100-250°C and the obtained compound of the formula III is a new compound. The acid acceptor is e.g. diazabicyclooctane. The compound of the formula I is produced by using 1-15mol of aniline based on 1mol of the compound of the formula III and reacting in a solvent such as acetonitrile at 0-120°C.


Inventors:
BERUNTO GARENKANPU
ROTAA ROOE
ARUBUREHITO MARUHORUTO
Application Number:
JP33016296A
Publication Date:
July 08, 1997
Filing Date:
November 27, 1996
Export Citation:
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Assignee:
BAYER AG
International Classes:
C07D231/16; A01N43/56; C07D231/14; (IPC1-7): C07D231/16; A01N43/56
Attorney, Agent or Firm:
Heiyoshi Odashima