To simply obtain a fluorine-containing compound by reacting an α- perfluoroalkylated alcohol with a Broensted acid in an aprotic solvent.
A perfluoroalkylsulfonic acid ester or perfluoroarylsulfonic acid ester of an α-perfluoroalkylated alcohol of the formula R1R2Rf1C-OSO2Rf2 [R1 and R2 are each H, an alkyl, an aromatic, an aralkyl, an alkenyl or an alkynyl or R1 and R2 together may form a ring; Rf1 and Rf2 are each a perfluoroalkyl or a perfluoro aromatic] is reacted with a Broensted acid of the formula Mx+mQy-n [Mx+ is a metal ion or polyatomic cation; Qy- is a conjugated base of the Broensted acid QHy; (x), (y), (m) and (n) are each an integer satisfying the formula xm=yn] in a solvent such as DMF at -100 to 200°C to provide the objective fluorine-containing compound of the formula (R1R2Rf1 C-)yQ (Q is a Broensted acid residue). The compound can be utilized as a synthetic intermediate for medicines and agrochemicals such as aticancer agents and enzyme inhibitors and functional materials such as ferroelectric liquid crystals.
HAGIWARA TOSHINORI
