Title:
PRODUCTION OF OPTICALLY ACTIVE ALCOHOL DERIVATIVE
Document Type and Number:
Japanese Patent JP3486685
Kind Code:
B2
Abstract:
PURPOSE: To produce an optically active alcohol derivative useful as an intermediate for agrochemicals, pharmaceuticals and organic electronic materials in a high optical purity by reacting a specific unsaturated compound with a silane compound in the presence of a transition metal complex containirjg a specific optically active compound as a ligand and oxidizing the reaction product.
CONSTITUTION: This optically active alcohol derivative of the formula VII is produced by reacting (A) an unsaturated compound off-formula I [R1 is a l-20C (halogen-substituted)alkyl or a 2-20C (halogen-substituted)alkoxyalkyl; A1, A2 and A3 each is group of the formula II, formula III, etc. (when A1 is a condensed ring, A2 is a monocyclic group and A1 is single bond and when A1 is a monocyclic group and P=1, A2 and A3 each is a monocyclic group); (n) is an integer of 0-10; (m) and (p) each is 0 or 1; (u) and (w) each is an integer of 0-3] with (B) a silane compound of formula V (X5 is H, an alkyl, etc.) in the presence of (C) a transition metal complex containing an optically active t-phosphine compound of the formula IV (R2 is a halogen, a lower alkoxy, etc.; R3 is an alkyl, etc.; R4 and R5 each is H, etc.) as a ligand and oxidizing the produced optically active organic silicon compound of the formula Vl.
Inventors:
Takayuki Higashii
Masayoshi Nanai
Yukari Fujimoto
Tsutomu Matsumoto
Masayoshi Nanai
Yukari Fujimoto
Tsutomu Matsumoto
Application Number:
JP8966394A
Publication Date:
January 13, 2004
Filing Date:
April 27, 1994
Export Citation:
Assignee:
Sumitomo Chemical Co., Ltd.
International Classes:
C07D237/08; B01J31/24; C07B61/00; C07C29/48; C07C33/24; C07C33/46; C07C41/30; C07C43/23; C07D213/06; C07D213/30; C07D215/20; C07D217/02; C07D239/26; C07D239/34; C07D239/74; C07D239/80; C07D241/12; C07D241/44; C07D401/04; C07D401/10; C07D403/04; C07D403/10; C07F7/08; (IPC1-7): C07D239/26; B01J31/24; C07C29/48; C07C33/24; C07C33/46; C07C41/30; C07C43/23; C07D213/06; C07D213/30; C07D215/20; C07D217/02; C07D237/08; C07D239/34; C07D239/74; C07D239/80; C07D241/12; C07D241/44; C07D401/04; C07D401/10; C07D403/04; C07F7/08
Attorney, Agent or Firm:
Takashi Kuboyama
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