PURPOSE: To obtain the subject high-yield product formulated with 100% of the active ingredient, simplified in production process and obviated in the necessity of its sterilization, by coarsely grinding a stock such as a crude drug followed by pulverization and then directly tableting the resultant fine particles.
CONSTITUTION: First, a stock of crude drug such as Panax ginseng C.A. Meyer is coarsely ground. Subsequently, the resultant coarse granules are pulverized into fine particles (pref. 0.5-10μm in diameter) which are then directly tableted to obtain the objective product. The pulverization is pref. carried out as follows: a jet mill is charged with the coarsely ground particles under supersonic air jet and the particles are ground into fine particles through mutual collision and their collision with the wall. It is recommended that the particles be sterilized along with the pulverization by heat generated due to high-speed rotation of the jet mill.
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