Title:
ニューロトロフィンの精製
Document Type and Number:
Japanese Patent JP4671372
Kind Code:
B2
Abstract:
Methods are provided for large scale purification of neurotrophins, including mature NGF, suitable for clinical use. The methods provide means to separate neurotrophins from various less desirable misprocessed, misfolded, size, glycosylated, or charge forms. Compositions of neurotrophins, including mature NGF, substantially free of these variants are also provided.
Inventors:
Burton, Lewis, Yi.
Schmelzer, Charles, Eitch.
Beck, Joanne, Tee.
Schmelzer, Charles, Eitch.
Beck, Joanne, Tee.
Application Number:
JP52291398A
Publication Date:
April 13, 2011
Filing Date:
November 14, 1997
Export Citation:
Assignee:
Genentech, Incorporated
International Classes:
C07K14/475; C07K1/20; C07K14/48
Domestic Patent References:
| JP5331198A | ||||
| JP6319549A | ||||
| JP6508036A | ||||
| JP6501617A |
Foreign References:
| WO1996032407A1 | ||||
| WO1996035718A1 | ||||
| WO1995016701A1 |
Other References:
社団法人日本生化学会編,「新生化学実験講座1 タンパク質I-分離・精製・性質-」,東京化学同人,1990,p.184-194
EXPERIMENTAL CELL RESERACH,1986,VOL.167,NO.2,P.550-558
EXPERIMENTAL CELL RESERACH,1986,VOL.167,NO.2,P.550-558
Attorney, Agent or Firm:
Sonoda Yoshitaka
Kobayashi Yoshinori
Kobayashi Yoshinori