Title:
ピリドン及びアザピリドン化合物、並びにそれらの使用方法
Document Type and Number:
Japanese Patent JP5832524
Kind Code:
B2
Abstract:
Pyridone and aza-pyridone compounds of Formula I are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
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Inventors:
Barbosa, Antonio J. M.
Brom Glen, Peter A.
Kuri, Kevin S.
Krishnamurti, Ravi
Kroff, Jeffrey E.
Lee, Sun Etch.
Mitchell Scott A.
Ortovin, Daniel
Schmid, Aaron See.
One, Xiao Jin
Sue, Jiangjun
Young, Wendy
Chan, Hongle
Jiao Dong
Zickin, Pavel Yi.
Brom Glen, Peter A.
Kuri, Kevin S.
Krishnamurti, Ravi
Kroff, Jeffrey E.
Lee, Sun Etch.
Mitchell Scott A.
Ortovin, Daniel
Schmid, Aaron See.
One, Xiao Jin
Sue, Jiangjun
Young, Wendy
Chan, Hongle
Jiao Dong
Zickin, Pavel Yi.
Application Number:
JP2013509305A
Publication Date:
December 16, 2015
Filing Date:
May 06, 2011
Export Citation:
Assignee:
Gilead Connecticut,Inc.
International Classes:
C07D471/14; A61K31/444; A61K31/496; A61K31/497; A61K31/4985; A61K31/501; A61K31/5025; A61K31/506; A61K31/53; A61K31/5377; A61K31/5383; A61K31/5386; A61K31/551; A61P1/04; A61P3/00; A61P5/00; A61P9/00; A61P11/00; A61P11/06; A61P17/00; A61P17/06; A61P19/02; A61P25/00; A61P29/00; A61P31/12; A61P35/00; A61P37/02; A61P37/06; A61P37/08; A61P43/00; C07D487/04; C07D495/04; C07D519/00
Domestic Patent References:
| JP2010504287A |
Foreign References:
| WO2009039397A1 | ||||
| WO2010000633A1 | ||||
| WO2009156284A1 | ||||
| WO2009137596A1 |
Attorney, Agent or Firm:
Kiyoaki Takita
Nakamura Narumi
Iwasakizaki Ario
Nakamura Narumi
Iwasakizaki Ario