Title:
GLI2を標的化するRNAアンタゴニスト
Document Type and Number:
Japanese Patent JP2011527901
Kind Code:
A
Abstract:
The present invention relates to oligomer compounds (oligomers), which target GLI2 mRNA in a cell, leading to reduced expression of GLI2. Reduction of GLI2 expression is beneficial for the treatment of certain medical disorders, such as hyperproliferative disorders, such as cancer.
Inventors:
Head Jern, My
Application Number:
JP2011518026A
Publication Date:
November 10, 2011
Filing Date:
July 15, 2009
Export Citation:
Assignee:
Enzon Pharmaceuticals, Incorporated
SANTARIS PHARMA A/S
SANTARIS PHARMA A/S
International Classes:
C12N15/113; A61K31/711; A61K48/00; A61P35/00; A61P43/00; C12N15/09
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka