Title:
ポックスウイルスゲノムに挿入された相同遺伝子を発現させる組換えポックスウイルス
Document Type and Number:
Japanese Patent JP5777199
Kind Code:
B2
Abstract:
The present invention relates to a recombinant poxvirus vector capable of expressing two or more homologous, foreign sequences, which derive from different variants of a microorganism, and which have a homology of 50% or above. The invention further relates to a method for preparing such recombinant poxvirus and the use of such recombinant poxvirus as medicament or vaccine. Additionally, a method for affecting preferably inducing an immune response in a living animal, including a human, is provided.
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Inventors:
Howley Paul
Ryler Zonya
Ryler Zonya
Application Number:
JP2010176512A
Publication Date:
September 09, 2015
Filing Date:
August 05, 2010
Export Citation:
Assignee:
Bavarian Nordic Actiselskab
International Classes:
C12N15/09; A61K35/36; A61K39/12; A61K39/21; A61K39/285; A61K39/29; A61K39/39; A61K48/00; A61P1/16; A61P31/12; A61P31/14; A61P31/18; A61P31/20; A61P35/00; A61P37/04; C07K14/07; C07K14/16; C07K14/18; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N7/00; C12N7/04; C12N15/863; C12P21/02; C12Q1/68; C12Q1/70; A61K39/00
Domestic Patent References:
| JP2000157292A |
Foreign References:
| WO2001068820A1 |
Other References:
Journal of Virological Methods,1999年,Vol.79,p.65-74
Gene,1996年,Vol.172,p.233-237
Journal of General Virology,1991年,Vol.72,p.1031-1038
Gene,1996年,Vol.172,p.233-237
Journal of General Virology,1991年,Vol.72,p.1031-1038
Attorney, Agent or Firm:
Mitsufumi Esaki
Blacksmith
Katsunori Uenishi
Ichiro Torayama
Blacksmith
Katsunori Uenishi
Ichiro Torayama