Title:
作用剤の輸送の制御及び吸収の向上のための逆ミセル送達システム
Document Type and Number:
Japanese Patent JP2005516013
Kind Code:
A
Abstract:
The invention can be summarized as follows. The present invention provides a reverse-micellar delivery system for enhanced absorption of an agent of interest across biological membranes such as the gastro-intestinal tract of mammals. The reverse-micelles comprise at least one ionic amphipathic compound, and at least one polar active agent ionizable in aqueous or physiological media. The delivery system facilitates transportation of the agent across the gastro-intestinal tract or other membranes and enhances the in-vivo release and availability of the agent(s) of interest within a fluid environment.
Inventors:
McGregor, Alexander
Application Number:
JP2003552266A
Publication Date:
June 02, 2005
Filing Date:
December 13, 2002
Export Citation:
Assignee:
McGregor, Alexander
International Classes:
A61K9/10; A61K9/107; A61K9/16; A61K9/20; A61K9/48; A61K31/155; A61K31/195; A61K31/34; A61K31/401; A61K45/00; A61K47/12; A61K47/18; A61K47/20; A61P1/04; A61P3/02; A61P3/10; A61P3/14; A61P5/00; A61P7/10; A61P7/12; A61P9/00; A61P9/12; A61P11/08; A61P13/00; A61P15/00; A61P15/18; A61P19/02; A61P21/00; A61P21/02; A61P23/02; A61P25/02; A61P25/08; A61P25/16; A61P25/18; A61P25/20; A61P25/24; A61P27/02; A61P29/00; A61P31/00; A61P31/04; A61P31/10; A61P31/12; A61P33/00; A61P33/02; A61P33/04; A61P33/06; A61P43/00; (IPC1-7): A61K9/10; A61K9/16; A61K9/20; A61K9/48; A61K45/00; A61K47/12; A61K47/18; A61K47/20; A61P3/02; A61P3/10; A61P3/14; A61P5/00; A61P7/10; A61P7/12; A61P9/00; A61P9/12; A61P11/08; A61P13/00; A61P15/00; A61P15/18; A61P19/02; A61P21/00; A61P21/02; A61P23/02; A61P25/02; A61P25/08; A61P25/16; A61P25/18; A61P25/20; A61P25/24; A61P27/02; A61P29/00; A61P31/00; A61P31/04; A61P31/10; A61P31/12; A61P33/00; A61P33/02; A61P33/04; A61P33/06; A61P43/00
Domestic Patent References:
| JPH11335266A | 1999-12-07 |
Foreign References:
| WO2001012155A1 | 2001-02-22 |
Attorney, Agent or Firm:
Takeshi Takada