Title:
RING-FUSED PYRIMIDINE DERIVATIVE
Document Type and Number:
Japanese Patent JP2007210886
Kind Code:
A
Abstract:
To provide a compound useful as a prophylactic or therapeutic agent for inflammatory diseases, allergic diseases, autoimmune diseases, etc., involving CC chemokine receptor 4 (CCR4).
The present inventors found that a ring-fused pyrimidine derivative having a saturated six membered hetero ring group such as piperidino or piperazino in which a saturated ring is bonded to the second position and having a substituted amino group at the fourth position has good activity as a function regulator of CCR4 and knew that the derivative is particularly useful as a therapeutic agent for inflammatory diseases such as dermatitis to complete the present invention.
COPYRIGHT: (C)2007,JPO&INPIT
Inventors:
KONO NORIYUKI
IGARASHI SUSUMU
KOGANEMARU YOHEI
YAMAZAKI SHINGO
HATTORI KAZUYUKI
MASUDA NAOYUKI
ISHIKAWA NORIKO
MIYAZAKI TAKAHIRO
IGARASHI SUSUMU
KOGANEMARU YOHEI
YAMAZAKI SHINGO
HATTORI KAZUYUKI
MASUDA NAOYUKI
ISHIKAWA NORIKO
MIYAZAKI TAKAHIRO
Application Number:
JP2004053121A
Publication Date:
August 23, 2007
Filing Date:
February 27, 2004
Export Citation:
Assignee:
ASTELLAS PHARMA INC
International Classes:
C07D239/95; A61K31/517; A61K31/519; A61K31/5377; A61P1/04; A61P3/10; A61P11/02; A61P11/06; A61P13/10; A61P17/00; A61P17/06; A61P19/02; A61P25/00; A61P25/02; A61P27/14; A61P29/00; A61P31/04; A61P35/00; A61P37/02; A61P37/06; A61P37/08; C07D401/04; C07D401/14; C07D403/12; C07D413/14; C07D471/04; C07D495/04
Attorney, Agent or Firm:
Morita Taku
Emiko Yano
Emiko Yano
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