To provide a running control device of a motor-assisted wheelchair which enables a user of the wheelchair to drive it rhythmically and nearly at a constant pitch even if the road condition changes.

An inertia running speed reduction detecting part 138 detects that the wheelchair is running forward by signals outputted from a rotation direction detecting switch 10, and calculates a speed reduction while the wheelchair is running by inertia based on the data from a speed detector 11. And a torque converting table 124, receiving data on the speed reduction from the inertial running speed reduction detecting part 138, outputs a larger torque instruction when the speed reduction is large, and a smaller torque instruction when the speed reduction is small, so that the timing when the speed becomes a prescribed one during inertial running is the same or almost the same without regard to the sloping angle of the road where the wheelchair is running. So a user of the wheelchair can the wheelchair rhythmically and almost at a constant pitch as the user starts driving when the speed of the wheelchair running by inertia becomes a prescribed one.