Title:
RUTHENIUM-DIAMINE COMPLEX AND PRODUCTION OF OPTICALLY ACTIVE ALCOHOL USING THE SAME AS CATALYST
Document Type and Number:
Japanese Patent JP3040353
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To obtain the new subject metal complex for production, etc., of optically active alcohols, useful as catalysts, etc., excellent in asymmetric yields in various organic synthetic reactions, especially hydrogen transfer type asymmetric reduction, etc., by bringing the complex to consist of a specific optically active ruthenium-diamine complex.
SOLUTION: The ruthenium-diamine complex is expressed by formula I [*is an asymmetric carbon atom; R1 and R2 are each an alkyl, a (substituted) phenol, a cycloalkyl or R1 together with R2 makes a (substituted) alicyclic ring; R3 is methanesulfonyl, trifluorosulfonyl, camphorsulfonyl, a (substituted) benzenesulfonyl, etc.; R4 is H or an alkyl; X is an (alkyl-substituted) aromatic compound; (m) and (n) are simultaneously 0 or 1] and is useful as a catalyst, etc., excellent in asymmetric yields in various organic synthetic reactions, especially an asymmetric reduction of the hydrogen transfer type, etc. The complex is obtained by reacting an optically active diamine expressed by formula II with tetrachlorobis (η6-p-cymen)nylruthenium, etc.
Inventors:
Takao Ikariya
Kazuhiko Matsumura
Shohei Hashiguchi
Akio Fujii
Ryoji Noyori
Kazuhiko Matsumura
Shohei Hashiguchi
Akio Fujii
Ryoji Noyori
Application Number:
JP28423396A
Publication Date:
May 15, 2000
Filing Date:
October 25, 1996
Export Citation:
Assignee:
Japan Science and Technology Agency
Nippon Steel Tube Co., Ltd.
Takasago International Corporation
Takeda GmbH
Nippon Steel Tube Co., Ltd.
Takasago International Corporation
Takeda GmbH
International Classes:
B01J31/18; C07B53/00; C07B61/00; C07C29/74; C07C31/133; C07C33/22; C07C35/02; C07C35/18; C07C35/32; C07C35/36; C07C35/37; C07C41/34; C07C43/23; C07C213/10; C07C215/68; C07D317/64; C07F15/00; (IPC1-7): C07F15/00; B01J31/18; C07B53/00; C07C29/74; C07C33/22; C07C35/18; C07C35/32; C07C35/36; C07C35/37; C07C41/34; C07C43/23; C07C213/10; C07C215/68; C07D317/64
Attorney, Agent or Firm:
Toshio Nishizawa