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Title:
プログラム細胞死(PD-1)に対するシングルドメイン抗体
Document Type and Number:
Japanese Patent JP7183163
Kind Code:
B2
Abstract:
The invention relates to PD-1 binding agents that do not block the interaction of PD-1 with its ligands, and the use of such binding agents in the treatment, prevention and detection of disease.

Inventors:
Brian edwards
Carolyn Edwards
James Leg
Martina Levandowska
Daniella Sidlek
Colette johnston
Christine rosant
Yumin Ten
Application Number:
JP2019536937A
Publication Date:
December 05, 2022
Filing Date:
January 08, 2018
Export Citation:
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Assignee:
Crescendo Biologics Limited
International Classes:
C07K16/28; A61K39/395; A61P25/00; A61P29/00; A61P31/12; A61P35/00; A61P37/00; C07K16/46; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/13; C12N15/63; C12P21/08; G01N33/53
Domestic Patent References:
JP2013521769A
Foreign References:
WO2009114335A2
WO2016106159A1
WO2016020856A2
WO2016062990A1
Other References:
YU GENG,SINGLE DOMAIN ANTIBODIES AGAINST IMMUNE CHECKPOINT TARGETS PD-1 AND PD-L1,IMMUNOME RESEARCH,2016年12月,V12 N2 (SUPPL),P47,https://www.longdom.org/proceedings/single-doman-antibodies-against-immune-checkpoint-targets-pd1-and-pdl1-6861.html,2ND INTERNATIONAL CONFERENCE ON ANTIBODIES AND THERAPEUTICS
Attorney, Agent or Firm:
Murayama Yasuhiko
Shinya Mihiro
Tatsuhiko Abe