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Title:
STENT COATING TO DISCHARGE MEDICINE AND METHOD
Document Type and Number:
Japanese Patent JP2007021247
Kind Code:
A
Abstract:

To provide the coating of a metallic stent prosthesis having a lattice structure with intervals, and a method.

The coating has a comparatively thin layer and the layer is comprised of a biologically stable elastomeric material. The elastomeric material has the prescribed quantity of a dispersed biologically active substance such as heparin particularly and has a non-thrombotic surface. In one embodiment of practice, a region comprised of a highly electronegative type is disposed on the surface by covering with fluoro-silicone. Thereby, the control of the elusion, particularly the initial discharge speed and the non-thrombotic nature is supported. An outer layer which is non-thrombotic because of heparin such as the one which has the covalent bonding with polyethylene glycol is presented.


Inventors:
DING NI
HELMUS MICHAEL N
Application Number:
JP2006286386A
Publication Date:
February 01, 2007
Filing Date:
October 20, 2006
Export Citation:
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Assignee:
BOSTON SCIENT LTD
International Classes:
A61F2/82; A61F2/86; A61F2/90; A61L27/00; A61L27/22; A61L31/00; A61L31/08; A61L31/10; A61L31/14; A61L31/16; A61L33/00; A61L33/10; A61F2/00
Domestic Patent References:
JPH05184666A1993-07-27
JPH07328124A1995-12-19
JPH0833718A1996-02-06
JPH11276596A1999-10-12
JPH07529A1995-01-06
JPH06218063A1994-08-09
JPH0833719A1996-02-06
JPH05502179A1993-04-22
JPH0889585A1996-04-09
Foreign References:
WO1995029647A21995-11-09
Attorney, Agent or Firm:
Kazuo Shamoto
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Okimoto Kazuaki