To obtain the stock management of toxic deadly poisonous and psychotropic drugs which enables accurate input through minimum input operations and can automate totalizing operation, the creation of legally submitted documents at the end of fiscal year, etc.

For a this management system for a storage box of toxic deadly poisonous, and psychotropic, drugs and the stock management having the management system, the management system for the storage box 5 is equipped with a matching means, which registers biological features of a user as data in a computer in advance and matches the registered data against biological feature data of the user by a matching machine, a unlocking means which unlocks a key box or the storage box with the matching signal of the matching means, and a storage box management means constituted, by connecting the matching machine and the sensor in the key box to a host equipped 1 by a communication cable. The stock management system is equipped with a measuring means, which measures the weights of toxic, deadly poisonous, and psychotropic drugs by a measuring instrument, an input means constituted by connecting the measuring instrument, a scanner for reading in bottle content information on the toxic, deadly poisonous, and psychotropic drugs in stock, and a seal printer for copying the seal information read in by the scanner to a seal to a terminal computer, and a stock management means constituted by connecting the terminal computer to the host computer.