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Title:
SULFONAMIDE COMPOUND FOR TREATING NEURODEGENERATIVE DISORDER
Document Type and Number:
Japanese Patent JP2008189673
Kind Code:
A
Abstract:

To provide a compound effective for treating neurodegenerative and/or neurological disorders such as Alzheimer's disease.

The sulfonamide compound is represented by formula I. This compound inhibits the production of A-peptide (accordingly, -secretase activity) in mammals including humans. Also, accordingly the compound of formula I and its pharmaceutically acceptable salt can function as a therapeutic agent in treating, for example, Alzheimer's disease in mammals including humans.


Inventors:
BRODNEY MICHAEL A
COFFMAN KAREN J
Application Number:
JP2008037819A
Publication Date:
August 21, 2008
Filing Date:
February 19, 2008
Export Citation:
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Assignee:
PFIZER PROD INC
International Classes:
A61K31/18; C07C311/19; A61K31/277; A61P1/04; A61P3/10; A61P9/10; A61P11/06; A61P17/06; A61P25/28; A61P29/00; A61P35/00; A61P37/06; A61P43/00; C07C311/29; C07C311/45; C07C317/28; C07C323/49; C07D215/233; C07D257/04; C07D263/32; C07D271/06; C07D285/06; C07D295/135
Attorney, Agent or Firm:
Yoshinobu Murofushi