Title:
スルホンアミド誘導体またはその薬学的に許容される酸付加塩
Document Type and Number:
Japanese Patent JP7170996
Kind Code:
B2
Abstract:
The present invention aims to provide a novel low-molecular-weight compound showing an orexin receptor agonist activity and expected to be useful as a prophylactic or therapeutic agent for narcolepsy and the like. The present invention provides a compound represented by the formula (I):wherein each symbol is as described in the description, or a pharmaceutically acceptable acid addition salt thereof, which has an orexin receptor agonist activity, and an orexin receptor agonist containing the compound or a pharmaceutically acceptable acid addition salt thereof.
Inventors:
Hiroshi Nagase
Takeshi Saito
Masashi Yanagisawa
Yoko Irukayama
Takeshi Saito
Masashi Yanagisawa
Yoko Irukayama
Application Number:
JP2019559662A
Publication Date:
November 15, 2022
Filing Date:
December 11, 2018
Export Citation:
Assignee:
National University Corporation University of Tsukuba
International Classes:
C07D239/10; A61K31/513; A61P3/04; A61P3/10; A61P9/02; A61P25/00; A61P25/24; A61P25/26; A61P43/00
Domestic Patent References:
| JP2002536447A | ||||
| JP2015521999A |
Foreign References:
| WO2016199906A1 | ||||
| WO2015088000A1 | ||||
| WO2016133160A1 |
Other References:
European Journal of Medicinal Chemistry,2004年,Vol.39,No.1,pp.49-58
Journal of Medicinal Chemistry,2015年,58(20),7931-7937
Journal of Medicinal Chemistry,2015年,58(20),7931-7937
Attorney, Agent or Firm:
Takashima Hajime
Mitsuyoshi Kamada
Kyoko Doi
Yaeko Tamura
Hirofumi Taima
Atsuko Akai
Tomiya Tosaki
Mitsuyoshi Kamada
Kyoko Doi
Yaeko Tamura
Hirofumi Taima
Atsuko Akai
Tomiya Tosaki